A novel ATAC-seq approach reveals lineage-specific reinforcement of the open chromatin landscape via cooperation between BAF and p63.

This demonstrated that BAF and p63-dependent target genes (fold change > 3 with depletion, FDR < 0.01) displayed highly significant overlap ( p = 2.1 × 10 −86 ), with 236 genes controlled jointly by both BAF and p63 (Fig. 2h ; Additional file 1 : Figure S2f, g; Additional file 2 : Table S2).

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