Enrichment of topology classes among DS-PQS associated with different functional loci While the structures of interstrand G4s with different topologies are yet to be determined crystallographically, structural differences between them may be significant for the specific functions of the quadruplex structures.
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G-Quadruplexes Involving Both Strands of Genomic DNA Are Highly Abundant and Colocalize with Functional Sites in the Human Genome.
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