Dimethyl fumarate treatment alters circulating T helper cell subsets in multiple sclerosis.

8 Further analysis revealed that memory T cells (CD45RO + ) were predominantly affected within the CD4 + and the CD8 + T cell population, resulting in a highly significant reduction in CD8 + as well as CD4 + memory T cells ( figure 1B ; 29.90%, p = 0.0079 and 31.13%, p = 0.0002, respectively).

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