This study also reported marginally significant evidence of association between the AA genotype of the rs2075786 SNP and cancer risk for carriers diagnosed with Lynch syndrome related-cancer diagnosed before the age of 45 years (RR=2.90; 95% CI=1.02–8.26; p=0.05) but we found no evidence of an association for that SNP and CRC risk before age 45 years.
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Genetic variants within the hTERT gene and the risk of colorectal cancer in Lynch syndrome.
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