The results reveal a highly significant over-representation of genes involved in cytokine and chemokine response pathways, such as: Cytokine Signaling in Immune system ( P -value 1.65e-27, Bayes factor 56.113, Reactome, 75–790); Interferon Signaling ( P -value 3.99 -23; Bayes factor 46.004, Reactome, 25_229) and NF-κB signaling pathway (2.63e-16, Bayes factor 30.286, KEGG, hsa_04064) in the set of genes under consideration (please see the online example for more details, http://lynx.ci.uchicago.edu/usecase.html ).
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Lynx: a knowledge base and an analytical workbench for integrative medicine.
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