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Faster Adaptation in Smaller Populations: Counterintuitive Evolution of HIV during Childhood Infection.

PLoS Comput Biol · 2016 · PMC4704780 · PMID 26741359

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a positive trendno p-value reported
This still supports the non-linear model of adaptation where immune responses vary from weak to strong, as either no distinct or a positive trend is expected.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.