Barely Significant
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The joint subclinical elevation of CRP and IL-6 is associated with lower health-related quality of life in comparison with no elevation or elevation of only one of the biomarkers.

Qual Life Res · 2016 · PMC4706574 · PMID 26195318

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highly significantno p-value reported
However, IL-6 still showed consistent and highly significant correlations to SF-36.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.