Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells.

J Transl Med · 2016 · PMC4706654 · PMID 26747087

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highly significantno p-value reported

Analyses of the quantified images indicated that the differences between tumor and normal tissues in total HDAC5 or HDAC6 levels protein levels (P < 0.0001) were all highly significant when comparing the 33 tumor samples with the 31 normal skin samples (Fig. 7 c).

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