A Germline Variant on Chromosome 4q31.1 Associates with Susceptibility to Developing Colon Cancer Metastasis.

We calculated the summary effect estimate using both fixed and random effect models, since the p-value for the test of homogeneity was marginally significant ( Table 3 ; p<0.10), which suggests some heterogeneity may be present and the variance between studies should be incorporated into the analyses to obtain confidence limits.

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