Divergent Effects of Dioxin- or Non-Dioxin-Like Polychlorinated Biphenyls on the Apoptosis of Primary Cell Culture from the Mouse Pituitary Gland.

Cisplatin (32 μM), a known apoptosis inducer in normal [ 37 ] and cancer cells [ 27 ], was used as a positive control and caused a highly significant induction of both early and late apoptosis of pituitary cells, as expected ( Fig 3A–3C ).

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