There was an increasing trend in both genders, which was more marked in females such that the ratio between genders increased from 5.07 (95% CI 4.48 to 5.73) in 1999 to 6.75 (95% CI 6.18 to 7.38) in 2012 ( figure 3 ).
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The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012.
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