Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease.

BMC Med Genomics · 2016 · PMC4722694 · PMID 26793951

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highly significantp = 1E-8actually significant

This result was highly significant (χ 2 = 33.68, p = 1E-8), with 52/166 (31.3 %) genes detected by proteomics showing increased expression in PD, compared with 518/929 (55.7 %) genes not detected by proteomics showing increased expression in PD.

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