marginally significantp = 0.051
In a Cox proportional regression model, PS, intensity of treatment and p27 retained statistical significance (HR = 2.363, 95% CI = 0.999–5.589, p = 0.050; HR = 2.550, 95% CI = 1.105–5.886, p = 0.028; HR = 3.743, 95% CI =1.064–13.169, p = 0.040, respectively) while cyclin D1 was marginally significant (HR = 1.070, 95% CI = 1.000–1.145, p = 0.051).