Notably, the protein ubiquitination pathway, which has been implicated in playing key roles in spermiogenesis, such as nucleosome removal and morphogenesis of the sperm [ 51 ], was also found to be highly significant by the ingenuity pathway analysis (Additional file 1 : Table S1).
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Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control.
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