Call Off the Dog(ma): M1/M2 Polarization Is Concurrent following Traumatic Brain Injury.

However, despite the highly complex inflammatory responses revealed by microarray [ 34 , 37 , 38 ] and bioinformatic approaches [ 16 , 39 ], there is an increasing trend to adopt a binary approach to categorize these reactions based upon decade-old understanding of in vitro -derived stimulus responses of isolated macrophages [ 5 ].

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