Barely Significant
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Epigenetic silencing of CREB3L1 by DNA methylation is associated with high-grade metastatic breast cancers with poor prognosis and is prevalent in triple negative breast cancers.

Breast Cancer Res · 2016 · PMC4727399 · PMID 26810754

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may not be significantno p-value reported
As similar results were not seen for luminal B and HER2 amplified breast cancers, the impact of low CREB3L1 expression may not be significant in the context of HER2 expression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.