Development of Novel Vaccines against Enterovirus-71.

Viruses · 2015 · PMC4728561 · PMID 26729152

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an increasing trendno p-value reported

In addition, there is an increasing trend to develop a bivalent VLP vaccine against both EV-A71 and CV-A16 as both viruses tend to co-circulate in major HFMD outbreaks.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.