Uncoupling of EGFR-RAS signaling and nuclear localization of YBX1 in colorectal cancer.

Statistical analyses of clinical parameters and survival analysis χ 2 -tests indicate that YBX1n positivity, but not YBX1c positivity, obtained in primary CRC reached a borderline significant negative correlation with the propensity to metastasize (Pearson— χ 2 : 4.09; P =0.043), that is, a lower number of metastasized tumors were scored YBX1n positive than expected (residual value: −6.4; Table 2A ).

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