Whereas, in T1D with complications IGFBP-1, -2, -3, and -6 showed highly significant associations (IGFBP-1: OR = 2.4, 4.1, 8.2; IGFBP-2: OR = 2.4, 4.8, 8.4; IGFBP-3: OR = 0.48, 0.52, 0.67; IGFBP-6: OR = 1.8, 3.6, 10, for 1Comp, 2Comp and 3Comp groups, respectively) (Table 3 ).
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IGF-Binding Proteins in Type-1 Diabetes Are More Severely Altered in the Presence of Complications.
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