Combined effect of hyperoxia and E 2 depletion with subsequent administration of E 2 lowered Nrf-2 nuclear level close to the margin of statistical significance, most probably due to small sample size ( p =0.065, hsham vs. hovxe) ( Fig. 6 A).
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Prominent role of exopeptidase DPP III in estrogen-mediated protection against hyperoxia in vivo.
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