The proportion of advanced gastric cancer in all enrolled patients was 85/147; at the endpoint, regorafenib group got significantly longer median PFS than placebo group (11 weeks versus 3.9 weeks, P < 0.0001) and the median OS (25 weeks versus 19.4 weeks, P = 0.11) also showed a positive trend [ 29 ].
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Current Molecular Targeted Therapy in Advanced Gastric Cancer: A Comprehensive Review of Therapeutic Mechanism, Clinical Trials, and Practical Application.
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