Loss of Endothelial Barrier in Marfan Mice (mgR/mgR) Results in Severe Inflammation after Adenoviral Gene Therapy.

PLoS One · 2016 · PMC4740453 · PMID 26840980

Europe PMC DOI

hedged sentences

0.0010

closest p · 0.0× alpha

0.0530

boldest claim

The sentences

highly significantp = 0.001actually significant

Compared to native mgR/mgR and Ad.hTIMP-1 treated WT aorta, the NI is highly significant greater in Ad.hTIMP-1 transduced mgR/mgR aorta (p = 0.001; p = 0.001).

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borderline significantp = 0.053so close (0.05 < p ≤ 0.1)

Compared to the untreated mgR/mgR Marfan aorta that did not have contact with adenovirus, the NI was significantly larger in Ad.hTIMP-1-treated (p<0.001) and borderline significant in Ad.β-Gal-treated mgR/mgR aorta (p = 0.053).

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