There are two symmetric regions flanking the origin of replication (0.55 and 4.2) that show a deviation from the general pattern of a decreasing trend of anabolic genes concentration towards the terminus.
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Relationship between digital information and thermodynamic stability in bacterial genomes.
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The sentences
This shows that the observed changes in entropies, even though very small, are highly significant and can safely be used to show differences in certain parts of the genome.