The search for cis-regulatory driver mutations in cancer genomes.

Oncotarget · 2015 · PMC4741709 · PMID 26356674

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highly significantno p-value reported

This research is highly significant as it is the first description of somatic driver mutations which affect enhancers in cancer [ 48 ] and thus uncovered a mechanism in carcinogenesis which is potentially common but yet to be characterized [ 46 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.