The highly significant P values are because of the fact that SNP-3.16732086 directly interrogates the functional polymorphism in exon 2 of GS3 , while the second and third MS-SNPs map 11.3 kb (SNP 3.16718013) and 16.8 kb (SNP 3.16712500) upstream of the transcriptional start site of GS3 , and explain 6% and 5.8% of the phenotypic variation, respectively ( Supplementary Data 3 ).
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