Chronic gastroesophageal reflux disease shares genetic background with esophageal adenocarcinoma and Barrett's esophagus.

Hum Mol Genet · 2016 · PMC4743691 · PMID 26704365

Europe PMC DOI

hedged sentences

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closest p · 0.0× alpha

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boldest claim

The sentences

close to being significantP = 9.5 × 10 −6actually significant

However, the ‘transforming growth factor beta (TGF-β)-activated receptor activity’ pathway (GO:0005024) came close to being significant ( P = 9.5 × 10 −6 ) in the combined GERD and BE analysis, followed by the ‘TGF-β receptor binding’ pathway (GO:0005160) ( P = 3.5 × 10 −5 ).

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an increasing trendno p-value reported

An increasing trend was observed in Nagelkerke's pseudo R 2 by increasing the proportion of top SNPs in the analysis (Fig. 1 C).

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