Barely Significant
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The novel adipokine progranulin counteracts IL-1 and TLR4-driven inflammatory response in human and murine chondrocytes via TNFR1.

Sci Rep · 2016 · PMC4745010 · PMID 26853108

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highly significantno p-value reported
This increase is highly significant after 7, 14, and 21 days of differentiation in comparison to undifferentiated cells (Day 0) ( Fig. 1 , upper panel).

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