highly significantP < 0.0001
A linear model analysis of the relative effects of RA and THAL on combined treatment with RA+THAL for all 214 snoRNA genes showed a highly significant influence of RA-induced snoRA expression ( P < 0.0001), and no influence of THAL-induced snoRA expression ( P = 0.94; power = 0.98 for an influence <5% that of RA).