highly significantP ≤ 0.01
Differences were considered significant at P ≤ 0.05 and highly significant at P ≤ 0.01.
Differences were considered significant at P ≤ 0.05 and highly significant at P ≤ 0.01.
We could clearly observe an increasing trend of the PARP1 amount caused, respectively, by treatment with ATRA, rapamycin and both drugs, confirming the immunofluorescence analysis results.