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Implications for determining the optimal treatment for locally advanced rectal cancer in elderly patients aged 75 years and older.

Oncotarget · 2015 · PMC4745806 · PMID 26160846

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may be significantno p-value reported
also suggested that although toxicities may be significant, elderly patients with rectal cancer of varied stages can be safely treated with RT or CRT with careful monitoring and frequent modification of treatment [ 13 ].

also in 13,097 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.