High Levels of 17β-Estradiol Are Associated with Increased Matrix Metalloproteinase-2 and Metalloproteinase-9 Activity in Tears of Postmenopausal Women with Dry Eye.

J Ophthalmol · 2016 · PMC4745962 · PMID 26904272

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an increasing trendno p-value reported

[ 36 ], which found an increasing trend in MMP-9 expression in dry eye subjects stratified by severity level.

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