On the other hand, among the tumor suppressor genes, CDKN2A/2B showed a highly significant silencing of the two mRNAs in the homozygously deleted samples (GIST_11, _150, _174 and _188) with respect to both CN = 2 and CN = 1 samples.
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Molecular characterization of metastatic exon 11 mutant gastrointestinal stromal tumors (GIST) beyond KIT/PDGFRα genotype evaluated by next generation sequencing (NGS).
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