Barely Significant
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Cancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?

Oncotarget · 2015 · PMC4747348 · PMID 26415231

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highly significantno p-value reported
These MM stem cells (MMSCs) are a controversial but highly significant issue in myeloma research because, in our opinion, they are at the root of the failure of anti-neoplastic chemotherapies to transform myeloma to a manageable chronic disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.