The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.

Mutagenesis · 2016 · PMC4748179 · PMID 26362870

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highly significantno p-value reported

L5178Y cells showed highly significant increases in MN induction and no decreases in cell viability could be observed at all ( 21 , 32 ).

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