How was the "right" gate determined in each case? Where the different time-points for a patient not stained in a single experiment or why do the staining patterns/signal strength look so different? Regarding the cross sectional analysis in Figure 4C , my concern remains that the differences seen in the few patients more than 2 years after treatment (already barely significant) might be driven by patient selection (exemplified by patients S11 and S12 with low memory percentages already pre and post treatment, potentially skewing the results for the 6 subjects included at more than 2 years post treatment).
← all excerpts
Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.
1
—
—