Indeed, due to the low prevalence of infection (and consequent very low Positive Predictive Value of any test), the generally low specificity of serodiagnostic tests (especially an issue in areas where contact with the parasite without cyst development and number of other diseases affecting the population may be significant), and the very low sensitivity of serodiagnosis in extra-hepatic CE (limiting the use of serology to diagnose CE in organs not explorable by ultrasound), the value of serological screenings is limited and should be conducted only after careful evaluation of the scientific question such studies want to answer.
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Comparison of the Diagnostic Accuracy of Three Rapid Tests for the Serodiagnosis of Hepatic Cystic Echinococcosis in Humans.
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The sentences
The performance of VIRapid HYDATIDOSIS was not statistically different from those of the ELISA test, while those of DIGFA (p = 0.045) and ADAMU-CE (p = 0.074) showed a borderline significant difference.