Barely Significant
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Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method.

PLoS One · 2016 · PMC4752462 · PMID 26872388

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a decreasing trendno p-value reported
Even though there was a decreasing trend in rate constants, we did not observe statistically significant difference in multiple comparisons.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.