During the RNA-Seq validation, many survival associations trended (p = 0.05–0.10) but failed to reach significance due to few cases having RNA-Seq data.
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Discovery of candidate tumor biomarkers for treatment with intraperitoneal chemotherapy for ovarian cancer.
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Reanalysis of previously reported survival outcomes to adjust for chemotherapy route as a potential confounder may be needed given that IP chemotherapy use was common among TCGA HGS OvCa patients and that receiving IP chemotherapy was associated with large and highly significant increases in PFS and OS.