marginal significancep < 0.10
A degree of efficacy consistency may be maintained by prohibiting subsequent subgroup testing if the overall test does not show any marginal significance, e.g., 0.025 < p < 0.10 (one-sided).
A degree of efficacy consistency may be maintained by prohibiting subsequent subgroup testing if the overall test does not show any marginal significance, e.g., 0.025 < p < 0.10 (one-sided).
The influence condition addresses the concern that the inference in the overall population may be unduly influenced by a highly significant subgroup treatment effect.