The unfolded protein response and its potential role in Huntington's disease elucidated by a systems biology approach.

F1000Res · 2015 · PMC4758378 · PMID 26949515

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highly significantno p-value reported

Inspecting the three human expression datasets, only the iPSC HD model showed a highly significant activation for all three UPR gene sets, whereas no consistent differential expression of the three UPR gene sets could be detected in blood and brain samples of HD patients.

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