Intestinal Epithelial Toll-Like Receptor 4 Signaling Affects Epithelial Function and Colonic Microbiota and Promotes a Risk for Transmissible Colitis.

Measurement of protein expression secreted by overnight culture of distal colon explants showed a notable trend toward greater IL-6, CXCL-10, and CCL2 secretion and lower IL-10 secretion in CH-WT mice than in SH-WT mice ( Fig. 7c ).

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