Even though the abscission delay was small when compared with overexpression of dominant-negative CHMP6 core (aa 1–152), it was highly significant and very similar to delays we observed upon depletion of the established cytokinetic regulator and ESCRT-I subunit TSG101.
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ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission.
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