Barely Significant
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Real-World Use of 3rd Line Therapy for Multiple Myeloma in Austria: An Austrian Myeloma Registry (AMR) Analysis of the Therapeutic Landscape and Clinical Outcomes prior to the Use of Next Generation Myeloma Therapeutics.

PLoS One · 2016 · PMC4777410 · PMID 26937956

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highly significantno p-value reported
There were highly significant changes to the use of novel agents over time (see Table 2 ) where an increase in the use of both bortezomib, lenalidomide and thalidomide, (from 2005 onwards) and their simultaneous use in combination therapies (from 2010 onwards) could be observed.

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