Characterization of IXINITY® (Trenonacog Alfa), a Recombinant Factor IX with Primary Sequence Corresponding to the Threonine-148 Polymorph.

Adv Hematol · 2016 · PMC4779506 · PMID 26997955

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a decreasing trendno p-value reported

This is supported by clinical data, as no new seroconversions have been identified in patients receiving new product, and patients who had previously seroconverted with measurable titers and who received trenonacog alfa (IXINITY) have shown a decreasing trend in titer values [ 28 ].

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