Early binding of both LMO2 and TAL1 is highly significant in regulatory elements whose chromatin is first opened in HBs, HEs, or HPs, and include binding prior to the appearance of overt DHS sites, which is indicative of TF-mediated enhancer priming (see pattern DHS_000110).
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Dynamic Gene Regulatory Networks Drive Hematopoietic Specification and Differentiation.
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