Ibandronate: The loading dose concept in the treatment of metastatic bone pain.

J Bone Oncol · 2016 · PMC4782017 · PMID 26998420

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highly significantno p-value reported

Discussion In the current study, we were able to show that the administration of loading-dose Ibandronate therapy (60 mg Ibandronate infused intravenously over 1 h for 3 consecutive days) resulted in a highly significant decrease in pain levels in patients suffering from metastatic bone disease.

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