Genome-wide Profiling Reveals Remarkable Parallels Between Insertion Site Selection Properties of the MLV Retrovirus and the piggyBac Transposon in Primary Human CD4(+) T Cells.

We detected a highly significant enrichment of SB insertions within 100 bp of the motifs ( Figure 6 ), consistent with a tethering mechanism, in which the transpositional complex is anchored to certain chromosomal sites bound by excess transposase molecules ( Supplementary Figure S7 ).

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