p63 expression confers significantly better survival outcomes in high-risk diffuse large B-cell lymphoma and demonstrates p53-like and p53-independent tumor suppressor function.

These phenomena may be explained by the remained MUT-p53-like function in the MUT-TP53 /p63 + cases, whereas TP63 mutations and expression of different p63 isoforms may not be significant factors as suggested by the previous studies [ 5 , 25 , 43 ] and our preliminary data of TP63 mutations in DLBCL (unpublished data).

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