The H3K27me3-associated genes within both groups showed highly significant overlap with MSigDb gene sets consisting of established PRC2 targets, and the most significant hit for both groups in the entire MSigDb database was “BENPORATH_ES_WITH_H3K27ME3” (data not shown).
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Ezh2 Controls an Early Hematopoietic Program and Growth and Survival Signaling in Early T Cell Precursor Acute Lymphoblastic Leukemia.
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