Evaluation of the role of remission status in a heterogeneous limited disease small-cell lung cancer patient cohort treated with definitive chemoradiotherapy.

In the multivariate analysis achievement of complete remission as a variable shows a trend for the prolonged time to progression ( p = 0.1, HR 1.48) and distant metastasis-free survival ( p = 0.06, HR 1.63) compared to partial responders and was highly significant compared to non-responders.

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Remission status was also analysed for its association with time to progression (TTP), distant metastasis-free survival (DMFS) and overall survival (OS) by univariate and multivariate Cox regression models after adjustment for other prognostic factors (borderline significant factors in the univariate analysis).

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